Listar por autor "Pineda, Laura M."
Mostrando ítems 1-4 de 4
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Coibacins A D, Antileishmanial Marine Cyanobacterial Polyketides with Intriguing Biosynthetic Origins
Balunas, Marcy J.; Grosso, Manuel F.; Villa, Francisco A.; Engene, Niclas; McPhail, Kerry L.; Tidgewell, Kevin; Pineda, Laura M.; Gerwick, Lena; Spadafora, Carmenza; Kyle, Dennis E.; Gerwick, William H. (2012-08-03)Four unsaturated polyketide lactone derivatives, coibacins A-D, were isolated from a Panamanian marine cyanobacterium, cf. Oscillatoria sp. The two different types of termini observed in these co-occurring metabolites, ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
Zhang, Xue-Qing; Spadafora, Carmenza; Pineda, Laura M.; Ng, Michelle G.; Sun, Ji-Hong; Wang, Wei; Wang, Chang-Yun; Gu, Yu-Cheng; Shao, Chang-Lun (2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
Zhang, Xue-Qing; Spadafora, Carmenza; Pineda, Laura M.; Ng, Michelle G.; Sun, Ji-Hong; Wang, Wei; Wang, Chang-Yun; Gu, Yu-Cheng; Shao, Chang-Lun (2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ... -
Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum
Torres-Mendoza, Daniel; Coronado, Lorena M.; Pineda, Laura M.; Guzmán, Héctor M.; Dorrestein, Pieter C.; Spadafora, Carmenza; Gutiérrez, Marcelino (2018-08-29)Chemical examination of the octocoral-associated Bacillus species (sp.) DT001 led to the isolation of pumilacidins A (1) and C (2). We investigated the effect of these compounds on the viability of Plasmodium falciparum ...