Listar por autor "Santamaría, Ricardo"
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Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién
Tayler, Nicole M.; Boya, Cristopher A.; Herrera, Liuris; Moy, Jamie; Ng, Michelle; Pineda, Laura; Almanza, Alejandro; Rosero, Sara; Coronado, Lorena M.; Correa, Ricardo; Santamaría, Ricardo; Caballero, Zuleima; Durant-Archibold, Armando A.; Tidgewell, Kevin J.; Balunas, Marcy J.; Gerwick, William H.; Spadafora, Alida; Gutiérrez, Marcelino; Spadafora, Carmenza (2019-04-02)Cocos nucifera (C. nucifera) (the coconut palm tree) has been traditionally used to fight a number of human diseases, but only a few studies have tested its components against parasites such as those that cause malaria. ... -
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease
Lakey-Beitia, Johant; González, Yisett; Doens, Deborah; Stephens, David E; Santamaría, Ricardo; Murillo, Enrique; Gutiérrez, Marcelino; L Fernández, Patricia; Rao, KS Jagannatha; Larionov, Oleg V; Durant-Archibold, Armando A (2017-01-01)Alzheimer's disease (AD) is the most common neurodegenerative disorder affecting the elderly population worldwide. Brain inflammation plays a key role in the progression of AD. Deposition of senile plaques in the brain ... -
A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS
González, Yisett; Doens, Deborah; Cruz, Héctor; Santamaría, Ricardo; Gutiérrez, Marcelino; Llanes, Alejandro; Fernández, Patricia L. (2018-10-05)he proteasome is an intracellular complex that degrades damaged or unfolded proteins and participates in the regulation of several processes. The immunoproteasome is a specialized form that is expressed in response to ... -
A Pseudopterane Diterpene Isolated From the Octocoral Pseudopterogorgia acerosa Inhibits the Inflammatory Response Mediated by TLR-Ligands and TNF-Alpha in Macrophages
González, Yisett; Doens, Deborah; Santamaría, Ricardo; Ramos, Marla; Restrepo, Carlos M.; Barros de Arruda, Luciana; Lleonart, Ricardo; Gutiérrez, Marcelino; Fernández, Patricia L. (2013-12-16)Several diterpenoids isolated from terrestrial and marine environments have been identified as important anti-inflammatory agents. Although considerable progress has been made in the area of anti-inflammatory treatment, ...