Browsing by Author "Sengupta, Shiladitya"
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Chromatin-bound oxidized α-synuclein causes strand breaks in neuronal genomes in in vitro models of Parkinson's Disease
Vasquez, Velmarini; Mitra, Joy; Hegde, Pavana M; Pandey, Arvind; Sengupta, Shiladitya; Mitra, Sankar; Rao, KS Jagannatha; Hegde, Muralidhar L (2019-09-01)Alpha-synuclein (α-Syn) overexpression and misfolding/aggregation in degenerating dopaminergic neurons have long been implicated in Parkinson’s disease (PD). The neurotoxicity of α-Syn is enhanced by iron (Fe) and other ... -
Chromatin-bound oxidized α-synuclein causes strand breaks in neuronal genomes in in vitro models of Parkinson’s disease
Vasquez, Velmarini; Mitra, Joy; Hegde, Pavana M; Pandey, Arvind; Sengupta, Shiladitya; Mitra, Sankar; Rao, KS Jagannatha; Hegde, Muralidhar L (2017-01-01)Alpha-synuclein (α-Syn) overexpression and misfolding/aggregation in degenerating dopaminergic neurons have long been implicated in Parkinson’s disease (PD). The neurotoxicity of α-Syn is enhanced by iron (Fe) and other ...