Browsing by Author "Shao, Chang-Lun"
Now showing items 1-3 of 3
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Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group
Shao, Chang-Lun; Feng Mou, Xiao; Cao, Fei; Spadafora, Carmenza; Glukhov, Evgenia; Gerwick, Lena; Yun Wang, Chang; Gerwick, William H. (2018-01-12)We reported previously the discovery of the potent antimalarial 40-membered macrolide bastimolide A (1) from the tropical marine cyanobacterium Okeania hirsute. Continued investigation has led to the discovery of a new ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
Zhang, Xue-Qing; Spadafora, Carmenza; Pineda, Laura M.; Ng, Michelle G.; Sun, Ji-Hong; Wang, Wei; Wang, Chang-Yun; Gu, Yu-Cheng; Shao, Chang-Lun (2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ... -
Discovery, Semisynthesis, Antiparasitic and Cytotoxic Evaluation of 14-Membered Resorcylic Acid Lactones and Their Derivatives
Zhang, Xue-Qing; Spadafora, Carmenza; Pineda, Laura M.; Ng, Michelle G.; Sun, Ji-Hong; Wang, Wei; Wang, Chang-Yun; Gu, Yu-Cheng; Shao, Chang-Lun (2017-09-18)Ten antifouling 14-membered resorcylic acid lactones 1–10 were isolated previously with low or trace natural abundance from the zoanthid-derived Cochliobolus lunatus fungus. Further optimization of fermentation conditions ...