Now showing items 1-5 of 5

    • American trypanosomiasis, or Chagas disease, in Panama: a chronological synopsis of ecological and epidemiological research 

      Rodriguez, Indra G.; Loaiza, Jose R. (2017-10-10)
      American trypanosomiasis, or Chagas disease, is a growing public health problem in Panama, and further forest degradation due to human population growth is expected to worsen the situation. Most people infected with the ...
    • Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién 

      Tayler, Nicole M.; Boya, Cristopher A.; Herrera, Liuris; Moy, Jamie; Ng, Michelle; Pineda, Laura; Almanza, Alejandro; Rosero, Sara; Coronado, Lorena M.; Correa, Ricardo; Santamaría, Ricardo; Caballero, Zuleima; Durant-Archibold, Armando A.; Tidgewell, Kevin J.; Balunas, Marcy J.; Gerwick, William H.; Spadafora, Alida; Gutiérrez, Marcelino; Spadafora, Carmenza (2019-04-02)
      Cocos nucifera (C. nucifera) (the coconut palm tree) has been traditionally used to fight a number of human diseases, but only a few studies have tested its components against parasites such as those that cause malaria. ...
    • Antiparasitic Compounds from the Panamanian Marine Bacterium Pseudomonas aeruginosa 

      Martínez-Luis, Sergio; Cherigo, Lilia; Spadafora, Carmenza; Gutiérrez, Marcelino (2019-01-01)
      Fractionation of the ethyl acetate extract of the bacterium Pseudomonas aeruginosa led to the isolation of five compounds, cyclo –(L-Phe-L-Pro) (1), 3-heptyl-3-hydroxy-1,2,3,4-tetrahydroquinoline-2.4-dione (2), ...
    • Antitrypanosomal Alkaloids from the Marine Bacterium Bacillus pumilus 

      Martínez, Luis sergio; Gómez, José Félix; Spadafora, Carmenza; Guzmán, Héctor M.; Gutiérrez, Marcelino (2012-09-18)
      Fractionation of the ethyl acetate extract of the marine bacterium Bacillus pumilus isolated from the black coral Antipathes sp. led to the isolation of five compounds: cyclo-(L-Leu-L-Pro) (1), 3-hydroxyacetylindole (2), ...
    • In vitro and in vivo experimental models for drug screening and development for Chagas disease 

      Romanha, Alvaro José; Lisboa de Castro, Solange; Correia Soeiro, Maria de Nazaré; Lannes-Vieira, Joseli; Ribeiro, Isabela; Talvani, André; Bourdin, Bernadette; Blum, Bethania; Olivieri, Bianca; Zani, Carlos; Spadafora, Carmenza; Chiari, Egler; Chatelain, Eric; Chaves, Gabriela; Calzada, José Eduardo; Bustamante, Juan Manuel; Freitas-Junior, Lucio H; Romero, Luz I; Terezinha Bahi, Maria; Lotrowska, Michel; Soares, Milena; Gumes Andrade, Sonia; Armstrong, Tanya; Degrave, Wim; De Araújo Andrade, Zilton (2010-03-02)
      Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of Latin America. Although the occurrence of acute cases sharply has declined due to Southern Cone Initiative efforts to control ...