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The effects of combined micron-/submicron-scale surface roughness and nanoscale features on cell proliferation and differentiation
(2011-02-08)
Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants. Previous studies have shown that surface roughness at the micro- and submicro-scales promotes osseointegration by enhancing ...
Confirmation of Anopheles (Anopheles) calderoni Wilkerson, 1991 (Diptera: Culicidae) in Colombia and Ecuador through molecular and morphological correlation with topotypic material
(2012-12)
The morphologically similar taxa Anopheles calderoni, Anopheles punctimacula, Anopheles malefactor and Anopheles guarao are commonly misidentified. Isofamilies collected in Valle de Cauca, Colombia, showed morphological ...
α-Glucosidase inhibitors from a mangrove associated fungus, Zasmidium sp. strain EM5-10
(2019-02-07)
Mangroves plants and their endophytes represent a natural source of novel and bioactive compounds. In our ongoing research on mangrove endophytes from the Panamanian Pacifc Coast, we have identifed several bio‑ active ...
Vacuolar Targeting of Cry1Ac and its Effects on Expression and Stability in Tobacco.
(2014-07-01)
Increasing heterologous expression of delta endotoxins of Bacillus thuringiensis in transgenic plants is being actively pursued as a
means to increase their efficacy and to delay insect resistance. To examine if vacuoles ...
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group
(2018-01-12)
We reported previously the discovery of the potent antimalarial 40-membered macrolide bastimolide A (1) from the tropical marine cyanobacterium Okeania hirsute. Continued investigation has led to the discovery of a new ...
Genome Sequences of Chikungunya Virus Isolates from Bolivia
(2020-04-16)
We generated nine coding-complete chikungunya virus genome sequences from blood samples collected during the early 2015 outbreak in Bolivia. Relative to other publicly available chikungunya sequences, the Bolivian samples ...
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015
(2016-10-08)
In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 ...
Malarial hemozoin: From target to tool
(2014-02-17)
Malaria is an extremely devastating disease that continues to affect millions of people each year. A distinctive attribute of malaria infected red blood cells is the presence of malarial pigment or so-called hemozoin. ...
A review on the wettability of dental implant surfaces I: Theoretical and experimental aspects
(2014-02-28)
The surface wettability of biomaterials determines the biological cascade of events at the biomaterial/ host interface. Wettability is modulated by surface characteristics, such as surface chemistry and surface topography. ...
L-Asparaginase a Biotherapeutic for Acute Lymphoblastic Leukemia-A Molecular Perspective
(2017-10-01)
L-asparaginase (L-asparagine amino hydrolase) is an enzyme which was clinically proved as an antitumor agent to treat acute lymphoblastic leukemia. It catalyzes L-asparagine hydrolysis to L-aspartate and ammonia, and the ...